Estradiol Benzoate EP Impurity E CAS 6045-53-0
| CAS No. | 6045-53-0 |
| Molecular Formula | C25H28O3 |
| Molecular Weight | 376.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Estradiol Benzoate EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Estradiol Benzoate EP Impurity E (CAS 6045-53-0) is a certified pharmaceutical impurity reference standard with the molecular formula C25H28O3 and a molecular weight of 376.49 g/mol.
Based on its molecular formula C25H28O3, Estradiol Benzoate EP Impurity E contains a steroid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 376.49 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C25H28O3 |
| Molecular Weight | 376.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Estradiol Standards
- Estradiol Benzoate EP Impurity D (CAS 983-30-2)
- Estradiol benzoate (CAS 50-50-0)
- Estradiol Impurity 33 (CAS CATO-C4X-163633)
- Estradiol Impurity 38 (CAS 4966-70-5)
- Estradiol Benzoate EP Impurity G (CAS 2393-53-5)
- Estradiol Benzoate EP Impurity F (CAS 95870-51-2)
- 17β-Estradiol-16,16,17-d3 3-Benzoate (CAS 1192354-74-7)
- Estradiol Valerate impurity 21 (CAS 1313382-32-9)
Recommended Standards
- Furan-2-ylmethyl 4'-heptyl-[1,1'-biphenyl]-4-carboxylate (CAS 920269-69-8)
- 9-[5-(5,5-Dimethyl-1,3-dioxan-2-yl)valeryl]phenanthrene (CAS 898756-50-8)
- Hypoestoxide(Sh) (CAS 88498-46-8)
- 9,9-Dimethyl-N2,N7-diphenyl-9H-fluorene-2,7-diamine (CAS 354987-86-3)
- Ibrutinib Impurity N2 (CAS 43191-23-7)
- Baricitinib Impurity 123 (CAS CATO-C4X-2260123)
- Peramivir Impurity 40 HCl (CAS 130931-84-9)
- Dronedarone Impurity 21 (CAS CATO-C4X-109221)
- 4-(Benzo[d][1,3]dioxol-5-yl)-5-((naphthalen-1-yloxy)methyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 1170884-67-9)
- Glycoprotein Hormone a (32-46) amide (H-3386.0001) (CAS 168782-25-0)
- 3-Amino-2-methylisonicotinaldehyde (CAS 1227581-90-9)
- 1-(4-Fluorophenyl)-4-iodo-1H-pyrazolo[3,4-b]pyridine (CAS 1356054-66-4)
- 2-[({5-[(2-Carboxybenzoyl)amino]-1-naphthyl}amino)carbonyl]benzoic acid (CAS 129684-51-1)
- Endo-Ala35-Tirzepatide (CAS CATO-CPTD788687)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com