Apremilast Impurity 36 CAS 608141-43-1
| CAS No. | 608141-43-1 |
| Molecular Formula | C12H19NO4S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Apremilast Impurity 36 (CAS 608141-43-1), a pharmacopoeial impurity reference standard (molecular formula C12H19NO4SC8H15NO3, MW 446.56 g/mol) used for the identification and quantification of trace impurities in APIs.
Apremilast Impurity 36 (C12H19NO4SC8H15NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Apremilast Impurity 36 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H19NO4S C8H15NO3 |
| Molecular Weight | 446.56 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Apremilast Standards
- Apremilast impurity 97 (CAS 1000342-08-4)
- Apremilast Impurity 86 (CAS 106860-70-2)
- Apremilast Impurity 33 HCl (CAS 1167056-61-2)
- Apremilast Impurity 108 (CAS 120-25-2)
- Apremilast Impurity 57 (CAS 1255909-25-1)
- Apremilast-d8 (CAS 1258597-45-3)
- Apremilast-d5 (CAS 1258597-47-5)
- Apremilast Impurity 56 (CAS 1284768-38-2)
Recommended Standards
- Pramipexole Impurity 46 (CAS 104617-49-4)
- Olopatadine Impurity 74 (CAS 2519517-78-1)
- Nicotinamide Impurity 18 (CAS 38806-38-1)
- N-(piperidin-3-ylmethyl)propionamide (CAS 886507-05-7)
- 2-(4-Chlorophenyl)-2-iodoacetophenone (CAS 898784-06-0)
- Tert-butyl (1-benzyl-4,5,6-trimethylpiperidin-3-yl)carbamate (CAS 1315365-57-1)
- 5-(tert-Butyl)-2-chlorobenzoxazole (CAS 1027076-19-2)
- 1'H-Spiro[piperidine-4,2'-quinazoline]-4'-thiol (CAS 1326871-48-0)
- 3-Bromo-5-cyano-4-fluorobenzenesulfonyl chloride (CAS 1804387-34-5)
- D-[Thr]5-Semaglutide (CAS CATO-C4X-2226245)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com