Lenvatinib Impurity 137 Chloride CAS 6118-33-8
| CAS No. | 6118-33-8 |
| Molecular Formula | C6H5N2O3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Lenvatinib Impurity 137 Chloride (CAS 6118-33-8), a pharmacopoeial impurity reference standard (molecular formula C6H5N2O3SCl, MW 220.63 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Lenvatinib Impurity 137 Chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 220.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Lenvatinib Impurity 137 Chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5N2O3S Cl |
| Molecular Weight | 220.63 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Lenvatinib Standards
- Lenvatinib Impurity 115 (CAS 106868-33-1)
- Lenvatinib Impurity 142 (CAS 1069122-99-1)
- Lenvatinib Impurity 48 (CAS 13021-02-8)
- Lenvatinib Impurity 71 (CAS 13066-95-0)
- Lenvatinib Impurity 93 (CAS 1378260-39-9)
- Lenvatinib Impurity N2 (CAS 13932-55-3)
- Lenvatinib Impurity 101 (CAS 1453-50-5)
- Lenvatinib Impurity 102 (CAS 15568-85-1)
Recommended Standards
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- Pazufloxacin Impurity 14 (CAS CATO-C4X-233214)
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- tert-Butyl 4-(4-iodobenzyl)-piperizine-1-carboxylate (CAS 1706437-45-7)
- 2-Chloro-4-fluoro-1-(2-methoxyethoxy)benzene (CAS 1036383-28-4)
- Osteoblast Activating Peptide (mouse, rat) (H-7262.0500) (CAS 1222950-80-2)
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