Lenvatinib Impurity N2 CAS 13932-55-3
| CAS No. | 13932-55-3 |
| Molecular Formula | C7H6O3 |
| Molecular Weight | 138.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lenvatinib Impurity N2.
As a process- or degradation-related impurity, Lenvatinib Impurity N2 (CAS 13932-55-3, C7H6O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Lenvatinib Impurity N2 (C7H6O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 138.12 g/mol, it falls into the low-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6O3 |
| Molecular Weight | 138.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
Related Lenvatinib Standards
- Lenvatinib Impurity 16 (CAS 69332-65-6)
- Lenvatinib Impurity 69 (CAS 615-66-7)
- Lenvatinib Impurity 119 (CAS CATO-C4X-1140119)
- Lenvatinib Impurity 121 (CAS CATO-C4X-1140121)
- Lenvatinib Impurity 130 (CAS 16026-77-0)
- Lenvatinib Impurity 132 (CAS 56962-01-7)
- Lenvatinib Impurity 33 (CAS 3964-52-1)
- Lenvatinib Impurity 68 (CAS 17609-80-2)
Recommended Standards
- 5,7-Dihydropyrano[3,4-c]pyrazol-4(1H)-one (CAS 1391732-41-4)
- 2-(2-Pyrazinyl)acetic Acid (CAS 140914-89-2)
- 2H-[1,3]dioxolo[4,5-b]pyridin-5-amine (CAS 1368345-12-3)
- 6,7-Dihydrobenzo[c][1,2,5]oxadiazol-4(5H)-one (CAS 142328-06-1)
- Fluorescein Impurity 3 (CAS 1428447-91-9)
- Osimertinib Impurity N1 (CAS 1421372-67-9)
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- 2-(3-Bromophenoxy)-N-(2,2,2-trifluoroethyl)acetamide (CAS 1252311-93-5)
- 2,2'-(((Disulfanediylbis(4,1-phenylene))bis(azanylylidene))bis(methanylylidene))diphenol (CAS 3430-53-3)
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- Akt/SKG Substrate Peptide (CAS 276680-69-4)
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