Ketoconazole Impurity 6 CAS 61397-56-6
| CAS No. | 61397-56-6 |
| Molecular Formula | C18H15BrCl2O4 |
| Molecular Weight | 446.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ketoconazole Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Ketoconazole Impurity 6 (CAS 61397-56-6), a pharmacopoeial impurity reference standard (molecular formula C18H15BrCl2O4, MW 446.12 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C18H15BrCl2O4, Ketoconazole Impurity 6 contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 446.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H15BrCl2O4 |
| Molecular Weight | 446.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl/Br-containing |
Related Ketoconazole Standards
- Ketoconazole impurity 34 (CAS CATO-C4X-147234)
- Ketoconazole Impurity 36 (CAS CATO-C4X-147236)
- Ketoconazole Impurity 9 (CAS 331949-30-5)
- Ketoconazole Impurity 10 (CAS 70894-66-5)
- Ketoconazole impurity 30 (CAS CATO-C4X-147230)
- Ketoconazole EP Impurity E (CAS 134071-44-6)
- Ketoconazole Impurity 14 (CAS 170210-50-1)
- Ketoconazole impurity 32 (CAS CATO-C4X-147232)
Recommended Standards
- Perfluoro(4-methyl-3,6-dioxaoct-7-ene)sulfonyl Fluoride (CAS 16090-14-5)
- trans-[2-Bromomethyl-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl Benzoate (CAS 61397-57-7)
- (7-Bromo-6-(bromomethyl)-2-methyl-4-oxoquinazolin-3(4H)-yl)methyl pivalate (CAS 140395-66-0)
- 1H-Indole-2,3-dione, 5-chloro-1-[(3,4-dichlorophenyl)methyl]-, 3-[O-(3-chloro-1-oxopropyl)oxime] (CAS 320420-75-5)
- Gliquidone Impurity 4 (CAS 191988-38-2)
- Sorafenib Impurity 36 (CAS CATO-C4X-112436)
- Thioctic acid Impurity 20 (CAS 2114407-83-7)
- 9,9-Dimethyl-N,N-di-p-tolyl-9H-fluoren-2-amine (CAS 132571-92-7)
- 2,4,6-Tris-(4-bromophenyl)[1,3,5]triazine (CAS 30363-03-2)
- Fmoc-Asp(OcHex)-OH (CAS 130304-80-2)
- 6,9-Difluoro-1-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (CAS 2408686-91-7)
- (S)-2-Amino-1-(4-((isopropyl(methyl)amino)methyl)piperidin-1-yl)-3-methylbutan-1-one (CAS 1307654-91-6)
- ethyl 5-amino-1-benzyl-1H-pyrazole-4-carboxylate (CAS 19867-62-0)
- Semaglutide Impurity 176 (CAS CATO-C4X-2226176)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com