2-((3-Fluoro-4-methoxyphenyl)amino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide CAS 1092829-93-0
| CAS No. | 1092829-93-0 |
| Molecular Formula | C23H18F4N4O2 |
| Molecular Weight | 458.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 458.41 g/mol gives 2-((3-Fluoro-4-methoxyphenyl)amino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-((3-Fluoro-4-methoxyphenyl)amino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide (CAS 1092829-93-0) is a high-purity analytical reference standard with the molecular formula C23H18F4N4O2 and a molecular weight of 458.41 g/mol.
The molecular framework of 2-((3-Fluoro-4-methoxyphenyl)amino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide (C23H18F4N4O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-((3-Fluoro-4-methoxyphenyl)amino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H18F4N4O2 |
| Molecular Weight | 458.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Fluoro Standards
- (11β)-9-Fluoro-11,17-dihydroxy-21-[(methylsulfonyl)oxy]pregna-1,4-diene-3,20-dione (CAS 382-66-1)
- Methyl 4-(3-(3-fluoro-4-methylbenzoyl)-4-hydroxy-5-oxo-1-(pyridin-3-ylmethyl)-2,5-dihydro-1H-pyrrol-2-yl)benzoate (CAS 618075-99-3)
- 4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-5-(4-isopropylphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618074-59-2)
- 4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-propoxyphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618073-92-0)
- N-(4-Fluoro-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)-2-iodobenzamide (CAS 865248-73-3)
- GDC-0623 (5-((2-Fluoro-4-Iodophenyl)amino)-N-(2-Hydroxyethoxy)imidazo[1,5-a]pyridine-6-Carboxamide) (CAS 1168091-68-6)
- 2-((2-Fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 869357-68-6)
- 2-(3-(2-((3-Fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetonitrile (CAS 1239875-86-5)
Recommended Standards
- N-(4-{[(2,4-Diamino-6-pteridinyl)methyl]amino}-3-fluorobenzoyl)-L-glutamic acid (CAS 85803-34-5)
- 5-((tert-Butyldimethylsilyl)oxy)-3-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole (CAS 1254473-78-3)
- N-(4-{[(2,4-Diamino-6-pteridinyl)methyl]amino}-2-fluorobenzoyl)-L-glutamic acid (CAS 85803-29-8)
- 5-[3-(tert-Butyl-1-(2,4-dichlorobenzyl)-1H-pyrazol-5-yl]-4-phenyl-4H-1,2,4-triazole-3-thiol (CAS 306937-09-7)
- tert-Butyl 4-chloro-5-methyl-1H-indole-1-carboxylate (CAS 442910-69-2)
- 5-((Ethylamino)methyl)-4-methylisoxazol-3(2H)-one (CAS 91305-13-4)
- N1-(2-Aminopropyl)propane-1,2-diamine (CAS 7356-00-5)
- 4-((4-Methylthiophen-2-yl)methyl)-1H-imidazole (CAS 779310-55-3)
- 6-(Prop-2-yn-1-ylamino)pyrimidin-2(1H)-one (CAS 193275-31-9)
- 1,3-Difluoro-2-(4-fluoro-5-iodo-2-methylphenoxy)-5-(trifluoromethyl)benzene (CAS 2244086-98-2)
- n-(4-Bromophenyl)-2,2,2-trifluoroacetamide (CAS 24568-11-4)
- 2-(3-(4-Fluorobenzamido)phenoxy)ethyl 4-fluorobenzoate (CAS 866008-26-6)
- 7-Methoxypyrazolo[1,5-a]pyridine-4-carboxylic acid (CAS 1009601-94-8)
- D-Trp25-Tirzepatide (CAS CATO-CPTD788909)
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