Clemastine Fumarate EP Impurity A CAS 61826-32-2
| CAS No. | 61826-32-2 |
| Molecular Formula | C21H26ClNO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Clemastine Fumarate EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Clemastine Fumarate EP Impurity A (CAS 61826-32-2), a pharmacopoeial impurity reference standard (molecular formula C21H26ClNOC4H4O4, MW 459.97 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Clemastine Fumarate EP Impurity A is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 459.97 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C21H26ClNO C4H4O4 |
| Molecular Weight | 459.97 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Clemastine Standards
- Clemastine Impurity 27 (CAS 10095-17-7)
- Clemastine EP Impurity A(Mixture of Diastereomers) (CAS 108825-05-4)
- Clemastine Impurity 28 (CAS 1333340-87-6)
- Clemastine EP Impurity B (CAS 1352549-49-5)
- Clemastine fumarate (CAS 14976-57-9)
- Clemastine (CAS 15686-51-8)
- Clemastine Impurity 26 (CAS 171296-35-8)
- Clemastine Impurity 4 (CAS 20763-27-3)
Recommended Standards
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Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com