Perampanel Impurity 37 CAS 61941-79-5
| CAS No. | 61941-79-5 |
| Molecular Formula | C6H7NO2 |
| Molecular Weight | 125.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Perampanel Impurity 37 (CAS 61941-79-5, C6H7NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Perampanel Impurity 37 (C6H7NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H7NO2 |
| Molecular Weight | 125.13 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 1 |
Related Perampanel Standards
- Perampanel Impurity 16 (CAS 381233-78-9)
- Perampanel Impurity 17 (CAS 172732-52-4)
- Perampanel Impurity 38 (CAS 142929-10-0)
- Perampanel impurity 43 (CAS CATO-C4X-243043)
- Perampanel Impurity 14 (CAS 4341-02-0)
- Perampanel Impurity N1 (CAS 2377611-18-0)
- Perampanel Impurity 51 (CAS 943739-90-0)
- Perampanel Impurity 30 (CAS 1284376-94-8)
Recommended Standards
- Relugolix Impurity 56 (CAS 1393722-34-3)
- Deferiprone Impurity 2 (CAS 17184-19-9)
- Relugolix Impurity 36 (CAS 7252-84-8)
- 5-Methylcytosine (CAS 554-01-8)
- Trimebutine Impurity N4 HCl (CAS 104743-23-9)
- Folic Acid Impurity 17 (CAS 712-30-1)
- Remimazolam Impurity 13 (CAS CATO-C4X-282313)
- 5-Chloro-4-fluoro -2-(trifluoromethyl)-1H-benzimidazole (CAS 89426-94-8)
- 2,4-Dichloro-6,6-dimethyl-8,9-dihydro-6H-[1,4]oxazino[4,3-e]purine (CAS 1382981-73-8)
- methyl 3-ethynylpyridine-2-carboxylate (CAS 1196156-66-7)
- 9,10-Phenanthrenequinone (CAS 84-11-7)
- Spiro[2.5]oct-4-ylamine hydrochloride (CAS 1965308-89-7)
- ethyl 3-cyclohexyl-2-methylprop-2-enoate (CAS 115901-78-5)
- Semaglutide impurity 266 (CAS CATO-C4X-2226266)
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