Temozolomide Impurity 12 CAS 6285-64-9
| CAS No. | 6285-64-9 |
| Molecular Formula | C9H11N5O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C9H11N5OHCl, Temozolomide Impurity 12 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 241.68 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Temozolomide Impurity 12 (CAS 6285-64-9, C9H11N5OHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Temozolomide Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H11N5O HCl |
| Molecular Weight | 241.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Temozolomide Standards
- Temozolomide Impurity 14 (CAS 100-34-5)
- Temozolomide Impurity 13 (CAS 100191-43-3)
- Temozolomide Impurity 15 (CAS 100607-08-7)
- Temozolomide Impurity 22 (CAS 1114912-01-4)
- Temozolomide EP Impurity B (CAS 113942-30-6)
- Temozolomide EP Impurity C (CAS 114601-31-9)
- Temozolomide Metabolite-MTIC-d3 (CAS 1185242-69-6)
- Temozolomide Metabolite-MTIC (CAS 1232679-46-7)
Recommended Standards
- Vericiguat Impurity 41 (CAS CATO-C4X-289641)
- Azilsartan Impurity 112 (CAS CATO-C4X-1096112)
- Biapenem Impurity 21 (CAS 153851-71-9)
- Landiolol Impurity 64 (CAS CATO-C4X-262164)
- 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride (CAS 38485-01-7)
- 2,8-Bis(diphenylphosphoryl)dibenzo[b,d]furan (CAS 911397-27-8)
- ∆1-Androstene-3α,17β-diol 17-Acetate (1.0mg/ml in Acetonitrile) (CAS 14291-94-2)
- 4-Nitro-4-aminodiphenyl Sulfone (CAS 1948-92-1)
- 2-(5-Bromo-2-oxopyridin-1(2h)-yl)-N-(tetrahydro-2h-pyran-4-yl)acetamide (CAS 1223189-48-7)
- D-Lys16-Tirzepatide (CAS CATO-CPTD788918)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com