Tadalafil Impurity 16 CAS 629652-44-4
| CAS No. | 629652-44-4 |
| Molecular Formula | C22H19ClN2O5 |
| Molecular Weight | 426.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Tadalafil Impurity 16 (CAS 629652-44-4), a pharmacopoeial impurity reference standard (molecular formula C22H19ClN2O5, MW 426.85 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C22H19ClN2O5, Tadalafil Impurity 16 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 426.85 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tadalafil Impurity 16 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H19ClN2O5 |
| Molecular Weight | 426.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tadalafil Standards
- Tadalafil impurity 10 (CAS 629652-40-0)
- Tadalafil Impurity 17 (CAS 629652-42-2)
- Tadalafil Impurity 37 (CAS 171489-59-1)
- Tadalafil Impurity 67 (CAS CATO-C4X-108767)
- Tadalafil Impurity 84 (CAS CATO-C4X-108784)
- Tadalafil Impurity N23 (CAS 951661-84-0)
- Tadalafil Impurity 24 (CAS 951661-81-7)
- Tadalafil Impurity 70 (CAS CATO-C4X-108770)
Recommended Standards
- Ethyl 2-amino-4-(4-chlorophenyl)-5-cyano-6-oxo-1-((6-oxocyclohex-1-en-1-yl)amino)-1,6-dihydropyridine-3-carboxylate (CAS 341965-82-0)
- 2-Chloro-1,8-diphenoxyanthracene-9,10-dione (CAS 61601-41-0)
- Ytterbium(II) iodide (CAS 19357-86-9)
- rel-Chloropretadalafil (CAS 171596-58-0)
- Alectinib impurity 24 (CAS 1256585-32-6)
- Enalapril Impurity 39 (CAS 2055735-10-7)
- Cholic Acid Impurity 40 (CAS CATO-C4X-116040)
- 2-((tert-Butoxycarbonyl)amino)-2,2-dicyclobutylacetic acid (CAS 1879039-27-6)
- 1-(2-methoxyethyl)-4-methyl-1h-pyraZol-3-amine (CAS 1344250-05-0)
- N-(tert-butyl)-4-fluorobenzamide (CAS 49834-29-9)
- (R)-(1,4-Dioxan-2-yl)methyl methanesulfonate (CAS 1170702-78-9)
- 2-Amino-6-fluoropyridine-4-sulfonyl chloride (CAS 1393547-89-1)
- Methyl (E)-3-chloro-2-cyanoacrylate (CAS 73619-75-7)
- Des-Gly29,30-Tirzepatide (CAS CATO-CPTD788944)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com