Valsartan Impurity 12 CAS 6306-52-1
| CAS No. | 6306-52-1 |
| Molecular Formula | C6H13NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 167.63 g/mol gives Valsartan Impurity 12 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Valsartan Impurity 12 (CAS 6306-52-1, C6H13NO2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Valsartan Impurity 12 (C6H13NO2HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Valsartan Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H13NO2 HCl |
| Molecular Weight | 167.63 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Valsartan Standards
- Valsartan Impurity 121 (CAS 1000986-63-9)
- (S)-(-)-Valsartan-d8 (valine-d8) (CAS 1089736-72-0)
- Valsartan-d9 (Major) (CAS 1089736-73-1)
- Valsartan Impurity 13 ( Valproic Acid EP Impurity A ) (CAS 109-52-4)
- Valsartan Impurity 35 HCl (CAS 1111177-20-8)
- Valsartan Impurity 9 (CAS 1111177-30-0)
- Valsartan Impurity 10 (CAS 114772-54-2)
- Valsartan Impurity 82 (CAS 1189547-11-2)
Recommended Standards
- Fluralaner Impurity 53 (CAS CATO-C4X-218053)
- Ambroxol Impurity 89 (CAS CATO-C4X-108589)
- Upadacitinib Impurity 147 (CAS CATO-C4X-2405147)
- Tenofovir Impurity 110 (CAS 20776-34-5)
- Methyl 4-iodo-1-isobutyl-1H-pyrazole-5-carboxylate (CAS 1354706-00-5)
- 1,1,1-trichloro-2-nitroethane (CAS 64326-81-4)
- 6-chloro-1-(prop-2-en-1-yl)-1H,4H,7H-pyrazolo[3,4-d]pyrimidin-4-one (CAS 2138003-96-8)
- 2-Tert-butyl-2,3-dihydro-1,4-benzodioxin-2-ol (CAS 106662-98-0)
- 1-Methyl-2-(pyridin-4-yl)pyrrolidin-3-amine (CAS 1339161-83-9)
- Endo-Gly4-Semaglutide (CAS CATO-C4X-222679)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com