Verapamil EP Impurity A DiHCl CAS 63434-11-7
| CAS No. | 63434-11-7 |
| Molecular Formula | C25H38N2O4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Verapamil EP Impurity A DiHCl.
Verapamil EP Impurity A DiHCl (CAS 63434-11-7), molecular formula C25H38N2O4HCl and molecular weight 467.05 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Verapamil EP Impurity A DiHCl is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 467.05 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H38N2O4 2*HCl |
| Molecular Weight | 467.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Verapamil Standards
- Verapamil Impurity N1 (CAS 102201-30-9)
- Verapamil Impurity 38 (CAS 114847-42-6)
- Verapamil D6 HCl (CAS 1185032-80-7)
- Verapamil-d7 Hydrochloride (CAS 1188265-55-5)
- Verapamil EP Impurity G (CAS 120-14-9)
- Verapamil EP Impurity J-D7 HCl (CAS 1216413-74-9)
- Verapamil EP Impurity B HCl (CAS 13078-76-7)
- (S)-(-)-Verapamil-d6 Hydrochloride (CAS 1329611-24-6)
Recommended Standards
- N-Nitroso Aceclofenac (CAS CATO-C4X-153110)
- 5-(Tert-butyl)-2-methylbenzaldehyde (CAS 66949-23-3)
- Methyl 4-methylenepyrrolidine-2-carboxylate (CAS 1296797-20-0)
- Ethyl 3-methyl-1-(propan-2-yl)-1H-pyrazole-4-carboxylate (CAS 1321594-80-2)
- 2-Methylimidazole-4-carboxylic Acid (CAS 1457-58-5)
- 5-Fluoro Paliperidone-d4 (CAS 1346602-73-0)
- 1-(Quinolin-4-yl)pyrrolidine-3-carboxylic acid (CAS 1284613-81-5)
- 1-(3-Hydroxy-7,8-dihydropyrido[4,3-c]pyridazin-6(5H)-yl)ethan-1-one (CAS 1071629-82-7)
- AT 1015 (CAS 190508-50-0)
- Liraglutide Impurity 13 TFA Salt (CAS CATO-C4X-199213)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com