Pimavanserin Impurity 21 CAS 646051-52-7
| CAS No. | 646051-52-7 |
| Molecular Formula | C14H13F2N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C14H13F2NHCl, Pimavanserin Impurity 21 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 269.72 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Pimavanserin Impurity 21 (CAS 646051-52-7, C14H13F2NHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Pimavanserin Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H13F2N HCl |
| Molecular Weight | 269.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Pimavanserin Standards
- Pimavanserin Impurity 2 (CAS 103907-97-7)
- Pimavanserin Impurity 1 (CAS 107456-06-4)
- Pimavanserin Impurity 20 (CAS 1134815-71-6)
- Pimavanserin Impurity 46 (CAS 1173710-95-6)
- Pimavanserin Impurity 51 (CAS 13221-89-1)
- Pimavanserin Acid Impurity (CAS 13362-94-2)
- Pimavanserin Impurity 3 (CAS 134227-41-1)
- Pimavanserin Impurity 35 (CAS 1791227-69-4)
Recommended Standards
- Rocuronium Bromide EP Impurity E (CAS 1190105-65-7)
- Ibrutinib Impurity 3 (CAS 1288338-96-4)
- Pimavanserin Impurity 68 (CAS CATO-C4X-193868)
- 2-[4-methyl-2-(methylsulfanyl)-1,3-thiazol-5-yl]acetic acid (CAS 77446-99-2)
- Tert-butyl 7-(methylamino)-5-azaspiro[2.4]Heptane-5-carboxylate (CAS 2306274-89-3)
- 3-Methyl-2-(phenylsulfonyl)-1H-indole (CAS 108665-95-8)
- N-Isopropyl-6-methyl-5-vinylpyridin-2-amine (CAS 1355182-06-7)
- 2-Hydroxy-3,6,7,10,11-pentakis(hexyloxy)triphenylene (CAS 156244-98-3)
- 1-(4-(Aminomethyl)phenyl)-2,2,2-trifluoroethanol (CAS 214759-63-4)
- CBP501 Affinity Peptide trifluoroacetate salt (CAS 1351804-17-5)
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