Entecavir EP Impurity F CAS 649761-24-0
| CAS No. | 649761-24-0 |
| Molecular Formula | C27H31N5O2Si |
| Molecular Weight | 485.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Entecavir EP Impurity F (CAS 649761-24-0), a pharmacopoeial impurity reference standard (molecular formula C27H31N5O2Si, MW 485.65 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Entecavir EP Impurity F (C27H31N5O2Si) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 485.65 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Entecavir EP Impurity F meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H31N5O2Si |
| Molecular Weight | 485.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 5 |
Related Entecavir Standards
- Entecavir Impurity 15 (CAS 142217-81-0)
- Entecavir Impurity 35 (CAS 1354695-82-1)
- Entecavir Impurity 46 (CAS CATO-C4X-107746)
- Entecavir Impurity 47 (CAS CATO-C4X-107747)
- Entecavir Impurity 48 (CAS CATO-C4X-107748)
- Entecavir Impurity 54 (CAS 1354695-86-5)
- Entecavir Impurity 55 (CAS 1354695-84-3)
- Entecavir Impurity 56 (CAS 1354695-85-4)
Recommended Standards
- Tetraacetyl Phytosphingosine (CAS 13018-48-9)
- Ebastine N-Oxide (CAS 1256285-71-8)
- N-mesityl-2-((4-(p-tolyl)-5-((p-tolylamino)methyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 335217-91-9)
- 2,6-Bis[(4R)-4,5-dihydro-4-tricyclo[3.3.1.13,7]dec-1-yl-2-oxazolyl]pyridine (CAS 934384-49-3)
- Apremilast Impurity 44 (CAS 2096492-44-1)
- Olaparib Impurity 11 (CAS 2250242-62-5)
- Indacaterol impurity 74 (CAS CATO-C4X-150074)
- 1-(Chloroacetyl)-2,2,4-trimethyl-1,2,3,4-tetrahydro-6-quinolinyl methyl ether (CAS 376371-15-2)
- 2-(4-Fluorophenyl)-1-(pyridin-3-yl)ethan-1-one (CAS 74767-71-8)
- 2-((4-(Trifluoromethyl)pyridin-2-yl)oxy)ethan-1-amine (CAS 1428233-16-2)
- 2-Methyl-n2-(2,2,2-trifluoroethyl)propane-1,2-diamine (CAS 1480292-75-8)
- 4-((Cyclohexyloxy)methyl)benzaldehyde (CAS 1443348-24-0)
- Meclozine EP Impurity B (CAS 119-56-2)
- D-[Phe6]-Semaglutide (CAS CATO-C4X-2226213)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com