Venetoclax Impurity 154 CAS 65080-57-1

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.65080-57-1
Molecular FormulaC9H14O
Molecular Weight138.21 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Venetoclax Impurity 154 CAS 65080-57-1 chemical structure

Description

Venetoclax Impurity 154 (CAS 65080-57-1) is a certified pharmaceutical impurity reference standard with the molecular formula C9H14O and a molecular weight of 138.21 g/mol.

Structurally, Venetoclax Impurity 154 (C9H14O) contains a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 138.21 g/mol, it falls into the low-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC9H14O
Molecular Weight138.21 g/mol
Purity97%+
StorageStore at 2-8°C
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityStable under recommended storage conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1975

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