Nicorandil CAS 65141-46-0
| CAS No. | 65141-46-0 |
| Molecular Formula | C8H9N3O4 |
| Molecular Weight | 211.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Nicorandil (C8H9N3O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Nicorandil (CAS 65141-46-0), molecular formula C8H9N3O4 and molecular weight 211.17 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9N3O4 |
| Molecular Weight | 211.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 3 |
Related Nicorandil Standards
- Nicorandil EP Impurity A (CAS 65141-47-1)
- Nicorandil Impurity 30 (CAS CATO-C4X-190730)
- Nicorandil Impurity 48 (CAS CATO-C4X-190748)
- Nicorandil Impurity 52 (CAS CATO-C4X-190752)
- Nicorandil Impurity 20 (CAS 70892-82-9)
- Nicorandil Impurity 24 (CAS 149415-43-0)
- Nicorandil Impurity 19 (CAS CATO-C4X-190719)
- Nicorandil Impurity 12 (CAS 83440-03-3)
Recommended Standards
- Lenalidomide Impurity 36 (CAS 1628915-10-5)
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- Mirabegron Impurity 76 (CAS 22573-24-6)
- Tert-butyl 1-fluoro-3,6-diazabicyclo[3.2.0]Heptane-6-carboxylate (CAS 1638763-79-7)
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- N-(3-Ethyl-4-fluorobenzo[d]thiazol-2(3H)-ylidene)-3-fluorobenzamide (CAS 868371-14-6)
- (3R,4R)-Methyl 4-methylpyrrolidine-3-carboxylate (CAS 1260603-20-0)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com