Nicorandil EP Impurity A CAS 65141-47-1
| CAS No. | 65141-47-1 |
| Molecular Formula | C8H9N3O4 |
| Molecular Weight | 211.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Nicorandil EP Impurity A (CAS 65141-47-1, C8H9N3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Nicorandil EP Impurity A is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 211.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Nicorandil EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9N3O4 |
| Molecular Weight | 211.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 3 |
Related Nicorandil Standards
- Nicorandil (CAS 65141-46-0)
- Nicorandil Impurity 30 (CAS CATO-C4X-190730)
- Nicorandil Impurity 48 (CAS CATO-C4X-190748)
- Nicorandil Impurity 52 (CAS CATO-C4X-190752)
- Nicorandil Impurity 20 (CAS 70892-82-9)
- Nicorandil Impurity 24 (CAS 149415-43-0)
- Nicorandil Impurity 19 (CAS CATO-C4X-190719)
- Nicorandil Impurity 12 (CAS 83440-03-3)
Recommended Standards
- Lenalidomide Impurity 36 (CAS 1628915-10-5)
- Metoclopramide Impurity 103 (CAS CATO-C4X-1415103)
- Ethyl 3-Hydroxy-4-nitrobenzoate (CAS 717-01-1)
- Fruquintinib Impurity 3 (CAS 854660-58-5)
- Tenofovir Disoproxil Impurity 61 (CAS CATO-C4X-107661)
- Sucralose EP Impurity G (CAS 105066-20-4)
- Ganaxolone Impurity 1 (CAS 1264737-31-6)
- 2-(3-Methylbutoxy)acetic acid (CAS 68298-29-3)
- Ethyl 3-methoxy-2-(trifluoromethyl)benzoate (CAS 1214329-33-5)
- 1-(5-Chloropyridin-3-yl)-n-methylmethanamine hydrochloride (CAS 2680615-89-6)
- (R)-2-Methyl-1-pyrrolidinecarboxylic acid benzylester (CAS 667420-95-3)
- 5-Bromo-1,1,1-trifluoropentan-2-one (CAS 121749-67-5)
- 2-(5-(4-(tert-Butyl)phenyl)-1H-pyrazol-3-yl)acetonitrile (CAS 1352482-63-3)
- Semaglutide impurity 54 (CAS CATO-C4X-222654)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com