Bedaquiline Impurity 53 CAS 654653-95-9
| CAS No. | 654653-95-9 |
| Molecular Formula | 2*C32H31BrN2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bedaquiline Impurity 53.
Bedaquiline Impurity 53 (CAS 654653-95-9) is a certified pharmaceutical impurity reference standard with the molecular formula C32H31BrN2O2 and a molecular weight of 555.52 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, Bedaquiline Impurity 53 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 555.52 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Bedaquiline Impurity 53 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | 2*C32H31BrN2O2 |
| Molecular Weight | 555.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bedaquiline Standards
- Bedaquiline Impurity 56 (CAS 1032468-56-6)
- Bedaquiline Impurity 68 (CAS 110486-69-6)
- Bedaquiline Impurity 21 (CAS 1228594-68-0)
- Bedaquiline Impurity 66 (CAS 1245907-31-6)
- Bedaquiline Impurity N21 (CAS 1298044-25-3)
- Bedaquiline Impurity 22 (CAS 1849588-75-5)
- Bedaquiline (1S,2S) Isomer Impurity 3 (CAS 1972612-60-4)
- Bedaquiline Impurity 8 (CAS 2122862-01-3)
Recommended Standards
- Sildenafil Impurity 279 (CAS CATO-C4X-1128279)
- Oxazepam impurity 4 (CAS 21882-29-1)
- Inosine impurity 7 (CAS CATO-C4X-28327)
- 4-(2-(Methylsulfinyl)phenyl)piperidine (CAS 161609-95-6)
- 1-Allyl-3-chloro-1H-1,2,4-triazole (CAS 1785763-47-4)
- (2-Phenylcyclobutyl)methanol (CAS 1780790-16-0)
- Tubocurarine Chloride Pentahydrate (CAS 6989-98-6)
- 1-(4-Fluorophenyl)-2-methylpropan-1-one (CAS 26393-91-9)
- N-alpha-(5-Fluoro-2,4-dinitrophenyl)-D-leucinamide (CAS 178065-30-0)
- Des-Ile12-Aib13-Tirzepatide (CAS CATO-CPTD788960)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com