Bedaquiline Impurity 8 CAS 2122862-01-3
| CAS No. | 2122862-01-3 |
| Molecular Formula | C32H32N2O2 |
| Molecular Weight | 476.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bedaquiline Impurity 8.
CATO supplies Bedaquiline Impurity 8 (CAS 2122862-01-3), a pharmacopoeial impurity reference standard (molecular formula C32H32N2O2, MW 476.61 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Bedaquiline Impurity 8 (C32H32N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Bedaquiline Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C32H32N2O2 |
| Molecular Weight | 476.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 2 |
Related Bedaquiline Standards
- Bedaquiline Impurity 38 (CAS CATO-C4X-116738)
- Bedaquiline Impurity N21 (CAS 1298044-25-3)
- Bedaquiline Impurity 22 (CAS 1849588-75-5)
- Bedaquiline Impurity 32 (CAS CATO-C4X-116732)
- Bedaquiline Impurity 33 (CAS CATO-C4X-116733)
- Bedaquiline Impurity 34 (CAS CATO-C4X-116734)
- Bedaquiline Impurity 35 (CAS CATO-C4X-116735)
- Bedaquiline Impurity 54 (CAS CATO-C4X-116754)
Recommended Standards
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- Doripenem Impurity 12 (CAS CATO-C4X-162112)
- Ethyl 7-methyl-5-(4-(methylthio)phenyl)-3-oxo-2-(3-phenylallylidene)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 6997-60-0)
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- 5-Bromo-3,3-dimethyl-3,4-dihydroquinolin-2(1h)-one (CAS 2090280-26-3)
- Immunstimulating Peptide, human (CAS 94773-24-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com