Nabumetone Impurity 2 CAS 65726-24-1
| CAS No. | 65726-24-1 |
| Molecular Formula | C15H18O2 |
| Molecular Weight | 230.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 230.30 g/mol gives Nabumetone Impurity 2 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Nabumetone Impurity 2 (CAS 65726-24-1, C15H18O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system, Nabumetone Impurity 2 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 230.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Nabumetone Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H18O2 |
| Molecular Weight | 230.30 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
Related Nabumetone Standards
Recommended Standards
- Felbinac Impurity 3 (CAS 26140-60-3)
- M-Terphenyl (CAS 92-06-8)
- Brivaracetam Impurity 13 (CAS 2252417-17-5)
- O-Terphenyl (CAS 84-15-1)
- Voriconazole Impurity 31 (CAS 1157981-64-0)
- Neratinib Impurity 58 (CAS CATO-C4X-113458)
- Domperidone Impurity 8 (CAS 53786-45-1)
- Ethyl 2-((tert-butoxycarbonyl)((1-(hydroxymethyl)cyclopropyl)methyl)amino)acetate (CAS 1998216-45-7)
- tert-Butyl 5-amino-2-methyl-1H-indole-1-carboxylate (CAS 867032-12-0)
- Ethyl 4-oxo-8-phenyl-4,6,7,8-tetrahydroimidazo[2,1-c][1,2,4]triazine-3-carboxylate (CAS 1038994-32-9)
- 1-(2,4-Dibromo-6-hydroxyphenyl)ethan-1-one (CAS 669767-20-8)
- 4-chloro-2-(1-oxo-1,3,4,6,7,8,9,10-octahydro-2H-cyclohepta[4,5]pyrrolo[1,2-a]pyrazin-2-yl)nicotinaldehyde (CAS 2387601-63-8)
- 1-(2-Bromo-1-(isopentyloxy)ethyl)-4-methylbenzene (CAS 1249435-80-0)
- Polymyxin B nonapeptide TFA (CAS 2220175-42-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com