Ranitidine EP Impurity B CAS 66356-53-4

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.66356-53-4
Molecular FormulaC10H18N2OS
Molecular Weight214.33 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ranitidine EP Impurity B CAS 66356-53-4 chemical structure

Description

As a certified reference material (CRM), Ranitidine EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

As a process- or degradation-related impurity, Ranitidine EP Impurity B (CAS 66356-53-4, C10H18N2OS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Ranitidine EP Impurity B (C10H18N2OS) contains an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Physical & Chemical Properties

Molecular FormulaC10H18N2OS
Molecular Weight214.33 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1975
Nitrogen Atoms2
Sulfur Atoms1

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