Thioctic Acid Impurity 44 CAS 6718-96-3
| CAS No. | 6718-96-3 |
| Molecular Formula | C16H28O4S4 |
| Molecular Weight | 412.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Thioctic Acid Impurity 44 is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Thioctic Acid Impurity 44 (CAS 6718-96-3, C16H28O4S4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C16H28O4S4, Thioctic Acid Impurity 44 contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 412.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Thioctic Acid Impurity 44 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H28O4S4 |
| Molecular Weight | 412.65 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Sulfur Atoms | 4 |
Related Thioctic Standards
- Thioctic Acid Impurity 24 (CAS CATO-C4X-152653)
- Thioctic acid Impurity 14 (CAS CATO-C4X-152614)
- Thioctic acid Impurity 15 (CAS CATO-C4X-152615)
- Thioctic acid Impurity 6 (CAS 108841-56-1)
- Thioctic Acid Impurity 7 (CAS CATO-C4X-15187)
- Thioctic acid Impurity 73 (CAS CATO-C4X-152673)
- Thioctic Acid Impurity 12 (CAS 916746-61-7)
- Thioctic acid Impurity 85 (CAS 13075-44-0)
Recommended Standards
- Calcipotriol Impurity 37 (CAS CATO-C4X-122237)
- Calcipotriol Impurity 22 (CAS 125732-36-7)
- Vitamin Impurity 34 (CAS 54573-75-0)
- Calcipotriol Impurity 20 (CAS 127516-23-8)
- Tirofiban Impurity 70 (CAS CATO-C4X-125470)
- Piperidine Impurity 19 (CAS CATO-C4X-239919)
- Pyridoxine impurity 93 (CAS 524-07-2)
- 7,7-Dimethyl-4,5-dioxo-10-thioxo-4,5,7,10-tetrahydro-[1,2]dithiolo[3,4-c]pyrrolo[3,2,1-ij]quinolin-2-yl benzoate (CAS 879618-23-2)
- N-(2-Acetyl-6-methoxyphenyl)acetamide (CAS 875258-00-7)
- 4-Methyl-4H-1,2,4-triazol-3-amine Hydroiodide (CAS 857371-41-6)
- 1H-pyrrolo[3,2-c]pyridine-4-carboxylic acid hydrochloride (CAS 1864063-95-5)
- (3S,5R)-3-ethynyl-3-hydroxy-1,5-dimethyl-pyrrolidin-2-one (CAS 2561461-00-3)
- 3,4-Bis(dicyclohexylphosphino)thiophene (CAS 1638677-61-8)
- Tau Peptide (301-315) trifluoroacetate salt (CAS 330456-48-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com