Thioctic Acid Impurity 24 CAS CATO-C4X-152653

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-152653
Molecular FormulaC16H28O4S4
Molecular Weight412.65 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Thioctic Acid Impurity 24 CAS CATO-C4X-152653 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

CATO supplies Thioctic Acid Impurity 24 (CAS CATO-C4X-152653), a pharmacopoeial impurity reference standard (molecular formula C16H28O4S4, MW 412.65 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Thioctic Acid Impurity 24 (C16H28O4S4) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC16H28O4S4
Molecular Weight412.65 g/mol
Purity>95%
StorageStore at room temperature, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
Sulfur Atoms4

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