Entacapone Impurity 30 CAS 148-53-8
| CAS No. | 148-53-8 |
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Entacapone Impurity 30 (CAS 148-53-8, C8H8O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Entacapone Impurity 30 (C8H8O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 152.15 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Entacapone Impurity 30 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Entacapone Standards
- Entacapone Impurity 26 (CAS 672-13-9)
- Entacapone EP Impurity C(Mixtures of tautomers) (CAS 116313-85-0)
- Entacapone impurity 38 (CAS CATO-C4X-162938)
- Entacapone Impurity N1 (CAS 15029-36-4)
- Entacapone Impurity 25 (CAS 6635-20-7)
- Entacapone Impurity 28 (CAS 2450-26-2)
- Entacapone Impurity 29 (CAS 2454-72-0)
- Entacapone Impurity 31 (CAS 80547-69-9)
Recommended Standards
- Levodopa Impurity 11 (CAS 85-43-8)
- Droxidopa Impurity 2 (CAS 5707-55-1)
- Olopatadine Impurity 29 (CAS 156-38-7)
- Atomoxetine Hydrochloride EP Impurity E (CAS 17199-29-0)
- Bilirubin impurity B1 (CAS CATO-C4X-15618)
- Varenicline Impurity C01 (CAS 357424-22-7)
- Terbinafine impurity 41 (CAS CATO-C4X-133841)
- 5-(Azepan-1-yl)furan-2-carbaldehyde (CAS 436088-58-3)
- Paclitaxel EP Impurity C (CAS 153415-45-3)
- DL-Citramalic Acid (CAS 2306-22-1)
- 2-Amino-N-(cyclopropylmethyl)acetamide (CAS 1016868-86-2)
- 1,4-Bis(trifluoromethyl)-5H-pyridazino[4,5-b]indole (CAS 111888-15-4)
- 2-(((Benzyloxy)carbonyl)amino)-3-(oxetan-3-yl)propanoic acid (CAS 2306263-41-0)
- Fibronectin Adhesion-Promoting Peptide (CAS 125720-21-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com