Halometasone impurity 11 CAS CATO-C4X-144611
| CAS No. | CATO-C4X-144611 |
| Molecular Formula | C22H27Cl3F2O5 |
| Molecular Weight | 515.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Halometasone impurity 11 (CAS CATO-C4X-144611), a pharmacopoeial impurity reference standard (molecular formula C22H27Cl3F2O5, MW 515.80 g/mol) used for the identification and quantification of trace impurities in APIs.
Halometasone impurity 11 (C22H27Cl3F2O5) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Halometasone impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H27Cl3F2O5 |
| Molecular Weight | 515.80 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
Related Halometasone Standards
- Halometasone impurity 16 (CAS CATO-C4X-144616)
- Halometasone Impurity 1 (CAS 23961-24-2)
- Halometasone Impurity N3 (CAS 23961-22-0)
- Halometasone Impurity 2 (CAS CATO-C4X-14462)
- Halometasone Impurity 8 (CAS 28895-70-7)
- Halometasone impurity 12 (CAS CATO-C4X-144612)
- Halometasone impurity 10 (CAS CATO-C4X-144610)
- Halometasone impurity 13 (CAS CATO-C4X-144613)
Recommended Standards
- 1,4-Bis(bromomethyl)-2,5-diiodobenzene (CAS 56403-29-3)
- Dodecanoic acid, 12-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-, 2,3-dihydroxypropyl ester (CAS 799812-64-9)
- 3-Hydroxy-2,4,6-triiodobenzoic Acid (CAS 53279-72-4)
- beta-Tauromuricholic Acid (CAS 25696-60-0)
- Cefmetazole Impurity 27 (CAS CATO-C4X-150727)
- Levocarnitine Impurity N9 (CAS 251460-19-2)
- Chlorphenamine Impurity 60 (CAS 1081516-68-8)
- N-(4-ethoxyphenyl)-2-(m-tolylthio)acetamide (CAS 329079-29-0)
- Tert-butyl 3-(4-nitro-1H-pyrazol-1-yl)piperidine-1-carboxylate (CAS 1201935-53-6)
- 2-(Diethylamino)ethyl 9H-fluorene-9-carboxylate hydrochloride (CAS 548-65-2)
- 4,4'-Dimethyl-[9,9'-bianthracene]-10,10'(9H,9'H)-dione (CAS 60019-18-3)
- 3-(1-(2-(Pyrrolidin-1-yl)ethyl)-1H-pyrazol-4-yl)benzoic acid (CAS 1206970-53-7)
- 1-Bromo-5-methylnaphthalene (CAS 20366-59-0)
- Antistasin-Related Peptide (CAS 161561-46-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com