Adrenaline Impurity 18 HCl CAS 67828-68-6
| CAS No. | 67828-68-6 |
| Molecular Formula | C9H11NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Adrenaline Impurity 18 HCl (CAS 67828-68-6), a pharmacopoeial impurity reference standard (molecular formula C9H11NO2HCl, MW 201.65 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Adrenaline Impurity 18 HCl (C9H11NO2HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 201.65 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H11NO2 HCl |
| Molecular Weight | 201.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Adrenaline Standards
- Adrenaline Impurity 34 (CAS 1095714-91-2)
- rac-Adrenaline EP Impurity D TFA salt (CAS 1095714-91-2(Free Base))
- Adrenaline Impurity 88 (CAS 139183-81-6)
- Adrenaline Impurity 42 (CAS 18191-22-5)
- Adrenaline Impurity 23 (CAS 1894824-44-2)
- Adrenaline Impurity 16 (CAS 2234-25-5)
- Rac-Adrenaline EP Impurity F (Epinephrine Sulfonic Acid) (CAS 26405-77-6)
- Adrenaline Impurity 17 HCl (CAS 29705-82-6)
Recommended Standards
- Amlodipine Impurity 56 (CAS 2418591-36-1)
- Ketoprofen Impurity 111 (CAS CATO-C4X-1471111)
- Entecavir Impurity 45 (CAS 3587-60-8)
- N-(3-(dimethylamino)propyl)-2-(piperazin-1-yl)acetamide (CAS 1018597-59-5)
- Betahistine Impurity 48 (CAS CATO-C4X-183848)
- 5-(5-Bromo-2-methoxyphenyl)thiophene-2-carbaldehyde (CAS 887986-96-1)
- 2-(Phenylsulfanyl)cyclopentan-1-one (CAS 52190-40-6)
- 3'-Methoxy-[1,1'-biphenyl]-2-amine hydrochloride (CAS 1082749-15-2)
- 5-Oxopyrrolidin-3-yl (3-methoxyphenyl)carbamate (CAS 88015-91-2)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com