Chloroquine Phosphate EP Impurity D (Chloroquine USP Related Compound G (Free Form)) CAS 68121-48-2
| CAS No. | 68121-48-2 |
| Molecular Formula | C18H26ClN3O |
| Molecular Weight | 335.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C18H26ClN3O, Chloroquine Phosphate EP Impurity D (Chloroquine USP Related Compound G (Free Form)) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 335.87 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Chloroquine Phosphate EP Impurity D (Chloroquine USP Related Compound G (Free Form)) (CAS 68121-48-2), a pharmacopoeial impurity reference standard (molecular formula C18H26ClN3O, MW 335.87 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Chloroquine Phosphate EP Impurity D (Chloroquine USP Related Compound G (Free Form)) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H26ClN3O |
| Molecular Weight | 335.87 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloroquine Standards
- Chloroquine-d4 Diphosphate Salt (CAS 1246815-14-4)
- Chloroquine Impurity 10 (CAS CATO-C4X-210410)
- Chloroquine (CAS 54-05-7)
- Chloroquine Impurity 1 (CAS 133860-75-0)
- Chloroquine Phosphate (CAS 1446-17-9)
- Chloroquine Dihydrochloride (CAS 3545-67-3)
- Chloroquine Diphosphate Hydrate (CAS 29791-25-1)
- Chloroquine-d5 Diphosphate (CAS 50-63-5 (unlabelled))
Recommended Standards
- Hydroxychloroquine impurity 78 (CAS CATO-C4X-183578)
- 2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethanol (CAS 118-42-3)
- Hydroxychloroquine R-isomer Impurity (CAS 137433-23-9)
- (2-Iodo-5-methoxy-4-(methoxycarbonyl)phenyl)boronic acid (CAS 1227633-23-9)
- Phloroglucinol Impurity 40 (CAS CATO-C4X-221740)
- Pyronaridine Impurity 23 (CAS CATO-C4X-297823)
- Meldonium EP Impurity B (CAS 44024-83-1)
- 55246-79-2 A830555 N-(4-methoxyphenyl)-N-methyl-carbamothioyl chloride N-(4-methoxyphenyl)-N-methylcarbamothioyl chloride (CAS 55246-79-2)
- Aristolochic Acid E (CAS 107259-48-3)
- 3-({1-[3-(4,5-DIHYDRO-1H-IMIDAZOL-2-YLAMINO)-PROPYL]-1H-INDAZOLE-4-CARBONYL}-AMINO)-2-(4-OXAZOL-2-YL-BENZENESULFONYLAMINO)-PROPIONIC ACID (CAS 1231023-78-1)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(3-methyl-1H-pyrazol-1-yl)furan-2-yl)boronate (CAS 2223046-02-2)
- 4-(4-Chlorophenyl)-6-(4-methylpiperazin-1-yl)-2-phenylpyrimidine-5-carbonitrile (CAS 320418-13-1)
- 930-35-8 0K9M0CR06O 1,3-Dithiole-2-thione EINECS 213-215-1 UNII-0K9M0CR06O (CAS 930-35-8)
- FLAG Epitope Peptide (CAS 98849-88-8)
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