Chloroquine Phosphate CAS 1446-17-9
| CAS No. | 1446-17-9 |
| Molecular Formula | C18H26ClN3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Chloroquine Phosphate.
Chloroquine Phosphate (CAS 1446-17-9) is a high-purity analytical reference standard with the molecular formula C18H26ClN3H3O4P and a molecular weight of 417.87 g/mol.
Structurally, Chloroquine Phosphate (C18H26ClN3H3O4P) contains a steroid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.5, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 417.87 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Chloroquine Phosphate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H26ClN3 H3O4P |
| Molecular Weight | 417.87 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloroquine Standards
- Chloroquine-d4 Diphosphate Salt (CAS 1246815-14-4)
- Chloroquine Impurity 1 (CAS 133860-75-0)
- Chloroquine Diphosphate Hydrate (CAS 29791-25-1)
- Chloroquine Dihydrochloride (CAS 3545-67-3)
- Chloroquine Diphosphate (CAS 50-63-5)
- Chloroquine-d5 Diphosphate (CAS 50-63-5 (unlabelled))
- Chloroquine (CAS 54-05-7)
- Chloroquine Phosphate EP Impurity D (Chloroquine USP Related Compound G (Free Form)) (CAS 68121-48-2)
Recommended Standards
- trans-Methyl 4-((tert-butoxycarbonyl)(methyl)amino)cyclohexanecarboxylate (CAS 400899-07-2)
- (3-(Pyridin-3-yl)-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-6-yl)methanamine (CAS 1422067-80-8)
- Methyl 21-hydroxyhenicosanoate (CAS 94035-98-0)
- 4-(Dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-amine (CAS 7520-92-5)
- 1-(4-Chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-51-4)
- 3-(5-Methyl-1,3,4-thiadiazol-2-yl)-2-phenylquinazolin-4(3H)-one (CAS 68142-70-1)
- 5-Amino-1-isopentyl-4-methylpyridin-2(1h)-one (CAS 1533116-51-6)
- 6-Bromo-2,4-dichloro-3-fluoroaniline (CAS 1360438-57-8)
- N-methyl-1-(5-methyl-6-(pyrrolidin-1-yl)pyridin-3-yl)methanamine (CAS 1355181-82-6)
- Semaglutide Impurity 6 (CAS 62-57-7)
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