Ruxolitinib Impurity 237 CAS CATO-C4X-2058237
| CAS No. | CATO-C4X-2058237 |
| Molecular Formula | C16H19N5 |
| Molecular Weight | 281.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ruxolitinib Impurity 237 (CAS CATO-C4X-2058237), a pharmacopoeial impurity reference standard (molecular formula C16H19N5, MW 281.36 g/mol) used for the identification and quantification of trace impurities in APIs.
Ruxolitinib Impurity 237 (C16H19N5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ruxolitinib Impurity 237 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H19N5 |
| Molecular Weight | 281.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Ruxolitinib Standards
- Ruxolitinib Impurity 229 (CAS CATO-C4X-2058229)
- Ruxolitinib Impurity 63 (CAS CATO-C4X-205863)
- Ruxolitinib Impurity 118 (CAS CATO-C4X-2058118)
- Ruxolitinib Impurity 107 (CAS CATO-C4X-2058107)
- Ruxolitinib Impurity 225 (CAS CATO-C4X-2058225)
- Ruxolitinib Impurity 14 (CAS CATO-C4X-205814)
- Ruxolitinib Impurity 36 (CAS CATO-C4X-205836)
- Ruxolitinib Impurity 135 (CAS CATO-C4X-2058135)
Recommended Standards
- N-Benzyl-9-butyl-9H-purin-6-amine (CAS 41945-74-8)
- ethyl 2-(methylthio)-4-(piperidin-1-yl)pyrimidine-5-carboxylate (CAS 100451-24-9)
- N-(4,6-dimethylpyrimidin-2-yl)-3,4-dihydroquinoline-1(2H)-carboximidamide (CAS 355824-85-0)
- 1018261-42-1 1-[(4-Isopropylphenyl)sulfonyl]piperidin-4-one MFCD10024617 (CAS 1018261-42-1)
- Oryzanol Impurity 5 (CAS CATO-C4X-28615)
- Progesterone EP Impurity K (CAS 17652-16-3)
- Selexipag Impurity 39 (CAS CATO-C4X-196139)
- N-(5-Amino-2-methylphenyl)-3-phenylpropanamide (CAS 953745-55-6)
- 2-(((Benzyloxy)carbonyl)amino)-2-(4,4-difluorocyclohexyl)acetic acid (CAS 1544167-82-9)
- 6-Bromo-4-chlorobenzo[d][1,3]dioxole (CAS 72736-55-1)
- 4-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid (CAS 1448891-80-2)
- tributyl-(5-tributylstannyl-2-furyl)stannane (CAS 193361-76-1)
- 1-(2-(2-(Phenylamino)pyridin-3-yl)pyrrolidin-1-yl)ethanone (CAS 1352518-03-6)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
Why CATO?
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