Paroxetine Impurity 50 CAS 69675-10-1
| CAS No. | 69675-10-1 |
| Molecular Formula | C12H14FN |
| Molecular Weight | 191.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Paroxetine Impurity 50.
Paroxetine Impurity 50 (CAS 69675-10-1) is a certified pharmaceutical impurity reference standard with the molecular formula C12H14FN and a molecular weight of 191.24 g/mol.
Paroxetine Impurity 50 (C12H14FN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Paroxetine Impurity 50 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14FN |
| Molecular Weight | 191.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Paroxetine Standards
- Paroxetine Impurity 25 (CAS CATO-C4X-103525)
- Paroxetine Impurity 21 (CAS 176022-03-0)
- Paroxetine Impurity 8 (CAS CATO-C4X-10358)
- Paroxetine Impurity N1 (Mixture of Diastereomers) (CAS 216690-19-6)
- Paroxetine EP Impurity I (CAS 125224-43-3)
- Paroxetine Impurity 19 (CAS 318279-38-8)
- Paroxetine impurity 20 (CAS 389573-45-9)
- Paroxetine Impurity 24 (CAS 105812-81-5)
Recommended Standards
- tert-Butyl (2-fluoro-2-methylpropyl)carbamate (CAS 879001-62-4)
- (4-(Pyridin-4-yl)thiazol-2-yl)methanamine (CAS 1019458-83-3)
- Antipyrine-d3 (CAS 65566-62-3)
- 3-(4-Oxo,-4-thiomorpholin-1-yl) Propanoic Acid (CAS 1020722-32-0)
- Baricitinib Impurity 87 (CAS CATO-C4X-226087)
- Ioversol Impurity 15 (CAS CATO-C4X-209115)
- Selumetinib Impurity N1 (CAS 917980-11-1)
- 2-[(5-Methyl-1,3,4-oxadiazol-2-yl)methyl]isoindole-1,3-dione (CAS 1225138-96-4)
- 1-(3-Chloro-4-methylphenyl)propan-1-ol (CAS 1270583-39-5)
- Pyridin-4-ol hydrochloride (CAS 26192-55-2)
- 3-(1-Pyrrolyl)thiophene-2-methanol (CAS 107073-27-8)
- 9-(Thiophen-2-yl)-2,4-bis(trifluoromethyl)-[1,2,4]triazolo[4,3-a][1,8]naphthyridine (CAS 338962-24-6)
- 2-(2-bromopyridin-3-yloxy)-5-(chloromethyl)pyridine (CAS 1065484-75-4)
- Galanin Message Associated Peptide (44-59) amide (CAS 125455-59-6)
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