Codeine-d3 CAS 70420-71-2
| CAS No. | 70420-71-2 |
| Molecular Formula | - |
| Molecular Weight | 302.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Codeine-d3 is closely related to deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Codeine-d3 (CAS 70420-71-2), molecular formula C18H18D3NO3 and molecular weight 302.38 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, Codeine-d3 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 302.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Codeine-d3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18D3NO3 |
| Molecular Weight | 302.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 100μg/mL in Methanol |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 1 |
Related Codeine Standards
- Codeine-D6 (CAS 1007844-34-9)
- Codeine (CAS 76-57-3)
- Codeine Phosphate Hemihydrate EP Impurity K (CAS 508-54-3)
- Codeine EP Impurity A (CAS 2859-16-7)
- Codeine 6-Methanesulfonate (1.0mg/ml in Acetonitrile) (CAS 22952-80-3)
- Codeine-6β-D-glucuronide (CAS 20736-11-2)
- Codeine-6-ß-D-glucuronide-D3 (CAS 219533-59-2)
- codeine hydrochloride (CAS 1422-07-7)
Recommended Standards
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- N-(3-(methylthio)-1H-1,2,4-triazol-5-yl)-1-phenylcyclopentane-1-carboxamide (CAS 1024119-77-4)
- Triheneicosanoin (CAS 26536-14-1)
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- (E)-1-(4-bromophenyl)-3-((((2-chlorophenyl)carbamoyl)oxy)(methyl)amino)prop-2-en-1-one (CAS 303151-52-2)
- Methyl 1-(3-hydroxyphenyl)cyclobutanecarboxylate (CAS 1257398-12-1)
- Methyl 2-(3,4-dichlorobenzoyl)benzoate (CAS 1443349-30-1)
- Goserelin EP Impurity E (CAS 147688-42-4)
- 3-methyl-2-(morpholin-4-yl)butan-1-amine (CAS 923176-80-1)
- Ethyl 3-oxo-2-phenyl-2,3-dihydro-1h-pyrazole-4-carboxylate (CAS 30588-33-1)
- 2-Chloro-1-[4-(3-fluorobenzenesulfonyl)piperazin-1-yl]ethan-1-one (CAS 879319-02-5)
- a-Bag Cell Peptide (1-8) (CAS 87549-53-9)
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