Nicardipine EP Impurity B DiHCl CAS 71784-27-5
| CAS No. | 71784-27-5 |
| Molecular Formula | C35H40N4O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Nicardipine EP Impurity B DiHCl (CAS 71784-27-5) is a certified pharmaceutical impurity reference standard with the molecular formula C35H40N4O6HCl and a molecular weight of 649.18 g/mol.
Structurally, Nicardipine EP Impurity B DiHCl (C35H40N4O6HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 17.0, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 649.18 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Nicardipine EP Impurity B DiHCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C35H40N4O6 2*HCl |
| Molecular Weight | 649.18 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Nicardipine Standards
- Nicardipine Impurity N11 (CAS 101-06-4)
- Nicardipine Impurity 24 (CAS 102993-38-4)
- Nicardipine Impurity N1 (CAS 10323-98-5)
- Nicardipine Impurity 36 (CAS 115972-93-5)
- (S)-Nicardipine HCl (CAS 118934-78-4)
- Nicardipine EP Impurity A HCl (CAS 1216817-27-4)
- Nicardipine O-Desmethyl (CAS 123973-71-7)
- Nicardipine Impurity 32 (CAS 134957-01-0)
Recommended Standards
- Ruxolitinib Impurity 189 (CAS 2761879-51-8)
- Cholic Acid Impurity 14 (CAS CATO-C4X-116014)
- Ketorolac Impurity 23 (CAS 141054-42-4)
- 2-(4-Bromothiophen-2-yl)-1,3-dioxolane (CAS 58267-85-9)
- 2-Cyclopentyl-5,6,7,8-tetrahydropyrido[3,4-d]pyridazin-1(2H)-one (CAS 1447961-34-3)
- 3-Nitro-2-(phenylamino)benzoic acid (CAS 54420-95-0)
- 2-Oxohistidine (CAS 181996-08-7)
- 2-(1-Pyrrolidinyl)-2-[4-(trifluoromethyl)phenyl]ethylamine (CAS 885950-66-3)
- 3-{[(3,5-Dimethylisoxazol-4-yl)methyl]thio}-5-methyl-4H-1,2,4-triazol-4-amine (CAS 931377-07-0)
- Semaglutide Impurity 187 (CAS CATO-C4X-2226187)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com