Trimetazidine EP Impurity D CAS 71989-96-3
| CAS No. | 71989-96-3 |
| Molecular Formula | C10H14O4 |
| Molecular Weight | 198.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Trimetazidine EP Impurity D (CAS 71989-96-3, C10H14O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Trimetazidine EP Impurity D (C10H14O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Trimetazidine EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H14O4 |
| Molecular Weight | 198.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
Related Trimetazidine Standards
- Trimetazidine Dihydrochloride EP Impurity C (CAS 2103-57-3)
- Trimetazidine Impurity 22 (CAS 86-81-7)
- Trimetazidine impurity 34 (CAS CATO-C4X-180334)
- Trimetazidine Impurity 20 (CAS 573-11-5)
- Trimetazidine Impurity 21 (CAS 69471-05-2)
- Trimetazidine Impurity 5 (CAS 1133-49-9)
- Trimetazidine Impurity 11 (CAS CATO-C4X-180311)
- Trimetazidine Impurity 12 (CAS 169506-15-4)
Recommended Standards
- Oseltamivir Impurity 287 (CAS CATO-C4X-1720287)
- Fenbufen impurity 7 (CAS CATO-C4X-19397)
- Conivaptan Impurity 1 (CAS 947-84-2)
- Carglumic Acid impurity 12 (CAS CATO-C4X-207912)
- Flunarizine EP Impurity C (CAS 90830-31-2)
- Trelagliptin Impurity 16 (CAS CATO-C4X-104616)
- Glycerol Impurity 43 (CAS 1188-64-3（free base）)
- 6-Methoxypyrazine-2-carboxylic Acid (CAS 24005-61-6)
- CAS 2389048-55-7 (CAS 2389048-55-7)
- 1-(3-Chloro-5-fluoropyridin-4-yl)ethanone (CAS 1256834-96-4)
- 4-Methyl-1,3-thiazolidine (CAS 33174-83-3)
- 4-(6-Methyl-4,8-dioxo-1,3,6,2-dioxazaborocan-2-yl)benzonitrile (CAS 1884492-36-7)
- Diethylenetriamine (CAS 111-40-0)
- Semaglutide Impurity 176 (CAS CATO-C4X-2226176)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com