Trimetazidine impurity 34 CAS CATO-C4X-180334
| CAS No. | CATO-C4X-180334 |
| Molecular Formula | C10H12O4 |
| Molecular Weight | 196.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Trimetazidine impurity 34 (CAS CATO-C4X-180334) is a certified pharmaceutical impurity reference standard with the molecular formula C10H12O4 and a molecular weight of 196.20 g/mol.
The molecular framework of Trimetazidine impurity 34 (C10H12O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C10H12O4 |
| Molecular Weight | 196.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Trimetazidine Standards
- Trimetazidine Dihydrochloride EP Impurity C (CAS 2103-57-3)
- Trimetazidine Impurity 22 (CAS 86-81-7)
- Trimetazidine EP Impurity D (CAS 71989-96-3)
- Trimetazidine Impurity 21 (CAS 69471-05-2)
- Trimetazidine Impurity 20 (CAS 573-11-5)
- Trimetazidine Impurity 5 (CAS 1133-49-9)
- Trimetazidine Impurity 11 (CAS CATO-C4X-180311)
- Trimetazidine Impurity 12 (CAS 169506-15-4)
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