Camptothecin Sodium Salt CAS 72517-83-0
| CAS No. | 72517-83-0 |
| Molecular Formula | C20H16N2O4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Camptothecin Sodium Salt.
Camptothecin Sodium Salt (CAS 72517-83-0), molecular formula C20H16N2O4Na and molecular weight 371.35 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Camptothecin Sodium Salt (C20H16N2O4Na) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H16N2O4 Na |
| Molecular Weight | 371.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 2 |
Related Camptothecin Standards
- (R)-Camptothecin (CAS 1083-11-0)
- (R)-(-)-Camptothecin (CAS 110351-92-3)
- Camptothecin Impurity N3 (CAS 119403-33-7)
- (S)-(+)-Camptothecin D5 (CAS 1329616-37-6)
- (R)-(-)-Camptothecin-d5 (CAS 1329793-44-3)
- 11-Ethyl Camptothecin (CAS 185807-29-8)
- Camptothecin Impurity 12 (CAS 19685-10-0)
- Camptothecin impurity 18 (CAS 19685-11-1)
Recommended Standards
- Calcium nitrate tetrahydrate (CAS 13477-34-4)
- Carfilzomib Impurity 67 (CAS 70637-27-3)
- tert-Butyl (4-bromo-2,6-dimethylphenyl)carbamate (CAS 1365988-24-4)
- 3-Amino-1-cyclopropylthiourea (CAS 122813-75-6)
- 3,4,5-trifluorobenzamide 3,4,5-tris(fluoranyl)benzamide 78324-75-1 A839393 (CAS 78324-75-1)
- 1-Iodo-4-(morpholin-4-yl)benzene 4-(4-iodophenyl)morpholine 87350-77-4 (CAS 87350-77-4)
- N-(4,5-Dihydro-1,3-oxazol-2-yl)sulfuric diamide (CAS 136810-62-3)
- Methyl (3S)-3-amino-3-(4-phenylphenyl)propanoate (CAS 933471-44-4)
- methyl 7-fluoro-3-methyl-2-oxo-1,3-benzoxazole-6-carboxylate (CAS 2387597-73-9)
- Mast Cell Degranulating (MCD) Peptide (CAS 32908-73-9)
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