Palbociclib Impurity 31 CAS 733039-20-8
| CAS No. | 733039-20-8 |
| Molecular Formula | C9H11BrClN3 |
| Molecular Weight | 276.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Palbociclib Impurity 31 (CAS 733039-20-8, C9H11BrClN3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution, Palbociclib Impurity 31 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 276.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Palbociclib Impurity 31 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H11BrClN3 |
| Molecular Weight | 276.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 3 |
Related Palbociclib Standards
- Palbociclib Impurity 67 (CAS 1823404-28-9)
- Palbociclib Impurity 110 (CAS 571189-23-6)
- Palbociclib Impurity 26 (CAS 1023594-50-4)
- Palbociclib Impurity 27 (CAS 1245914-05-9)
- Palbociclib Impurity 28 (CAS 571188-59-5)
- Palbociclib Impurity 6 (CAS 1023594-49-1)
- Palbociclib Impurity 199 (E-Isomer) (CAS CATO-C4X-1125199)
- Palbociclib Impurity 138 (CAS CATO-C4X-1125138)
Recommended Standards
- Propyl 5-bromo-2-chlorobenzamide (CAS 892018-30-3)
- n-[1-(4-bromophenyl)ethyl]-2-chloroacetamide (CAS 91687-65-9)
- Afoxolaner impurity 11 (CAS CATO-C4X-31381)
- N-[1-(2-bromophenyl)ethyl]-2-chloroacetamide (CAS 790272-21-8)
- Cefazedone impurity 18 (CAS CATO-C4X-117118)
- Etoposide Impurity 31 (CAS CATO-C4X-202431)
- Marbofloxacin Impurity 11 (CAS CATO-C4X-180011)
- 2'-Bromo-14H-spiro[dibenzo[c,h]acridine-7,9'-fluorene] (CAS 1303969-20-1)
- Relugolix Impurity 53 (CAS 68957-94-8)
- 5-Chloro-2-ethoxybenzaldehyde (CAS 27682-64-0)
- 3-Nitro-1-(3-phenylpropyl)-1h-pyrazole (CAS 1240569-56-5)
- 1-(1-Phenylcyclopentyl)ethan-1-ol (CAS 101266-82-4)
- 1-(3,4-Dichlorophenyl)-3-(3-(dimethylamino)phenyl)urea (CAS 94201-85-1)
- [y-Glu15]-Semaglutide Impurity 134 (CAS CATO-C4X-2226134)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com