Roxadustat Impurity 76 CAS 74717-81-0
| CAS No. | 74717-81-0 |
| Molecular Formula | C16H14O5 |
| Molecular Weight | 286.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Roxadustat Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Roxadustat Impurity 76 (CAS 74717-81-0) is a certified pharmaceutical impurity reference standard with the molecular formula C16H14O5 and a molecular weight of 286.28 g/mol.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, Roxadustat Impurity 76 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 286.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C16H14O5 |
| Molecular Weight | 286.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
Related Roxadustat Standards
- Roxadustat Impurity 98 (CAS 1572439-66-7)
- Roxadustat Impurity 164 (CAS CATO-C4X-2213164)
- Roxadustat Impurity 43 (CAS CATO-C4X-221343)
- Roxadustat Impurity 129 (CAS CATO-C4X-2213129)
- Roxadustat Impurity 18 (CAS 2376195-48-9)
- Roxadustat Impurity 160 (CAS CATO-C4X-2213160)
- Roxadustat Impurity 12 (CAS CATO-C4X-221312)
- Roxadustat Impurity N14 (CAS 2243809-28-9)
Recommended Standards
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- Remimazolam Impurity 14 (CAS CATO-C4X-282314)
- Clopidogrel Impurity 104 (CAS CATO-C4X-1029104)
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- Methyl 3-{[(2-amino-4-methyl-5-pyrimidinyl)carbonyl]amino}-2-thiophenecarboxylate (CAS 339020-63-2)
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- (R)-1-(Furan-2-yl)-2-hydroxypropan-1-one (CAS 152723-24-5)
- 2-(Morophlin-4-yl)-1,2,3,4-tetrahydronaphthalene (CAS 126684-45-5)
- Semaglutide impurity 89 (CAS CATO-C4X-222689)
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