Roxadustat Impurity 164 CAS CATO-C4X-2213164
| CAS No. | CATO-C4X-2213164 |
| Molecular Formula | C16H15ClO3 |
| Molecular Weight | 290.74 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Roxadustat Impurity 164 (CAS CATO-C4X-2213164), a pharmacopoeial impurity reference standard (molecular formula C16H15ClO3, MW 290.74 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C16H15ClO3, Roxadustat Impurity 164 contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 290.74 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H15ClO3 |
| Molecular Weight | 290.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Roxadustat Standards
- Roxadustat Impurity 43 (CAS CATO-C4X-221343)
- Roxadustat Impurity 160 (CAS CATO-C4X-2213160)
- Roxadustat Impurity 12 (CAS CATO-C4X-221312)
- Roxadustat Impurity N14 (CAS 2243809-28-9)
- Roxadustat Impurity 76 (CAS 74717-81-0)
- Roxadustat Impurity 64 (CAS 1509958-11-5)
- Roxadustat Impurity 9 (CAS 1421312-35-7)
- Roxadustat Impurity 99 (CAS CATO-C4X-221399)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com