Sulbactam Impurity 20 CAS 75527-88-7
| CAS No. | 75527-88-7 |
| Molecular Formula | C8H10BrNO5S |
| Molecular Weight | 312.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Sulbactam Impurity 20 (CAS 75527-88-7, C8H10BrNO5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Sulbactam Impurity 20 (C8H10BrNO5S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 312.14 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H10BrNO5S |
| Molecular Weight | 312.14 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Sulbactam Standards
- Sulbactam EP Impurity C (CAS 75527-87-6)
- Sulbactam Impurity 11 (CAS 79703-02-9)
- Sulbactam Impurity 12 (CAS 79611-43-1)
- Sulbactam Impurity 24 (CAS CATO-C4X-175624)
- Sulbactam EP Impurity G（Sodium Salt） (CAS CATO-C4X-17569)
- Sulbactam Impurity 16 (CAS CATO-C4X-175616)
- Sulbactam Impurity 36 (CAS CATO-C4X-175636)
- Sulbactam Impurity 31 (CAS CATO-C4X-175631)
Recommended Standards
- 5-Ethynyl-6-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-ol (CAS 2763159-03-9)
- 4,4,5,5-Tetramethyl-2-((1R,2S)-2-(4-(trifluoromethyl)phenyl)cyclopropyl)-1,3,2-dioxaborolane (CAS 2102308-70-1)
- 2-Iodo-N-((1-methyl-1h-pyrrol-2-yl)methyl)aniline (CAS 1040054-73-6)
- 4,4,5,5-tetramethyl-2-((1R,2R)-2-(3-(trifluoromethyl)phenyl)cyclopropyl)-1,3,2-dioxaborolane (CAS 2246414-66-2)
- Atorvastatin Impurity 141 Calcium Salt (CAS 1046378-58-8)
- Bromfenac Impurity 52 (CAS CATO-C4X-200252)
- Carfilzomib Impurity 92 (CAS CATO-C4X-102292)
- Methyl 2-chloro-6-methylnicotinate (CAS 53277-47-7)
- L32-1-2’β-Ala (CAS CATO-C4X-35402)
- (10E,12Z)-10,12-Octadecadienoic Acid Methyl Ester (CAS 21870-97-3)
- Cariprazine Impurity 63 (CAS CATO-C4X-240863)
- (5-(4-Fluorobenzyl)-2,4-dihydroxyphenyl)(isoindolin-2-yl)methanone (CAS 2134571-29-0)
- (2-Phenoxyphenyl)triphenylsilane (CAS 18847-88-6)
- (Des-Thr?)-Glucagon trifluoroacetate salt (CAS 1802078-27-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com