Bromfenac Impurity 52 CAS CATO-C4X-200252

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-200252
Molecular FormulaC15H10BrNO
Molecular Weight300.15 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Bromfenac Impurity 52 CAS CATO-C4X-200252 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 300.15 g/mol gives Bromfenac Impurity 52 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Bromfenac Impurity 52 (CAS CATO-C4X-200252) is a certified pharmaceutical impurity reference standard with the molecular formula C15H10BrNO and a molecular weight of 300.15 g/mol.

Bromfenac Impurity 52 (C15H10BrNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC15H10BrNO
Molecular Weight300.15 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentBr-containing
Nitrogen Atoms1

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