Carfilzomib Impurity 92 CAS CATO-C4X-102292
| CAS No. | CATO-C4X-102292 |
| Molecular Formula | C15H20N2O2 |
| Molecular Weight | 260.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Carfilzomib Impurity 92 (CAS CATO-C4X-102292, C15H20N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Carfilzomib Impurity 92 (C15H20N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Carfilzomib Impurity 92 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H20N2O2 |
| Molecular Weight | 260.33 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Carfilzomib Standards
- Carfilzomib Impurity 47 (CAS 72080-89-8)
- Carfilzomib Impurity 87 (CAS CATO-C4X-102287)
- Carfilzomib Impurity 34 (CAS 247068-81-1)
- Carfilzomib Impurity 55 (CAS 2177287-70-4)
- Carfilzomib Impurity 11 (CAS 247068-82-2)
- Carfilzomib Impurity 75 (CAS 2381627-87-6)
- Carfilzomib Impurity 50 (CAS 129603-01-6)
- CarfilzomiB impurity 12 (CAS 100564-78-1)
Recommended Standards
- 4,4''-Diamino-p-terphenyl (CAS 3365-85-3)
- Milnacipran impurity 32 (CAS 3026111-66-7)
- tert-butyl (4,6-dimethyl-1H-indol-5-yl)carbamate (CAS CATO-C3D-263259)
- Rosuvastatin Impurity 146 (CAS 148809-28-3)
- Nicergoline Impurity 27 (CAS 2061916-37-6)
- Amiodarone Impurity 38 (CAS 138320-26-0)
- Palbociclib Impurity 122 (CAS CATO-C4X-1125122)
- 2-Hydroxypyridin-4(1H)-one (CAS 29212-35-9)
- 6-Iodo-9H-purin-2-amine (CAS 19690-23-4)
- 2-(3-Chloro-4-methyl-phenyl)-1,3-benzoxazol-5-amine (CAS 429649-92-3)
- Isopropyl 2-bromobenzoate (CAS 59247-52-8)
- 2-(2-Chlorophenyl)-2,3-dihydro-1,3-dioxo-1H-isoindole-5-carboxylic acid (CAS 160878-86-4)
- L-phenylalanine, 1-(phenylsulfonyl)-l-prolyl-4-[[5-[(aminoiminomethyl)amino]-1-oxopentyl]amino]-, hcl (1:1) (CAS 1689542-67-3)
- Retatrutide (CAS 2381089-83-2)
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