Ibuprofen Impurity 73 CAS 75625-99-9

Description

The occurrence of Ibuprofen Impurity 73 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Ibuprofen Impurity 73 (CAS 75625-99-9), a pharmacopoeial impurity reference standard (molecular formula C13H16O2, MW 204.26 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Ibuprofen Impurity 73 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 204.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Ibuprofen Impurity 73 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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