Cholesterol Impurity 37 CAS 7591-17-5
| CAS No. | 7591-17-5 |
| Molecular Formula | C27H46O2 |
| Molecular Weight | 402.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Cholesterol Impurity 37 (CAS 7591-17-5) is a certified pharmaceutical impurity reference standard with the molecular formula C27H46O2 and a molecular weight of 402.65 g/mol.
The molecular framework of Cholesterol Impurity 37 (C27H46O2) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Cholesterol Impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H46O2 |
| Molecular Weight | 402.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
Related Cholesterol Standards
- Cholesterol-5α,6α-epoxide (CAS 1250-95-9)
- Cholesterol Impurity 13 (CAS 34310-88-8)
- Cholesterol Impurity 19 (CAS 566-46-1)
- Cholesterol Impurity 24 (CAS 26654-78-4)
- Cholesterol Impurity 25 (CAS 26358-75-8)
- Cholesterol Impurity 28 (CAS 70223-10-8)
- Cholesterol Impurity 26 (CAS 4505-68-4)
- Cholesterol 4alpha-Methyl 7-En Analog (CAS 481-25-4)
Recommended Standards
- 7α-Hydroxy Cholesterol (CAS 566-26-7)
- (25R)-26-?Hydroxycholesterol (CAS 20380-11-4)
- 25-Hydroxy Cholesterol (CAS 2140-46-7)
- 7β-Hydroxy Cholesterol (CAS 566-27-8)
- Cefminox Impurity 14 (CAS 51138-06-8)
- Carbidopa EP Impurity E (CAS 52514-63-3)
- Propranolol Impurity 10 (CAS 27610-48-6)
- N-(3-Cyclopropoxy-6-methoxypyridin-2-yl)methanesulfonamide (CAS 1243386-33-5)
- Ethyl 2-bromo-5-cyano-3-methylbenzoate (CAS 1805189-11-0)
- 6-Benzyl 1-methyl 2-[(tert-butoxycarbonyl)amino]-4-oxohexanedioate (CAS 1379524-46-5)
- (4-(1-(4-Ethylpiperazin-1-yl)ethyl)phenyl)boronic acid hydrochloride (CAS 1704069-35-1)
- (6-{4-[(4-Chloro-phenyl)-hydrazonomethyl]-phenyl}-4-trifluoromethyl-pyridin-2-yl)-dimethyl-amine (CAS 1311283-99-4)
- (S)-2-(4-(tert-butoxycarbonyl)-3-methyl-2-oxopiperazin-1-yl)acetic acid (CAS 959571-65-4)
- Liraglutide Impurity 22 (CAS 536721-25-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com