Nicardipine Impurity 25 CAS 76258-21-4

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.76258-21-4
Molecular FormulaC16H14N2O7
Molecular Weight346.29 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Nicardipine Impurity 25 CAS 76258-21-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 346.29 g/mol gives Nicardipine Impurity 25 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Nicardipine Impurity 25 (CAS 76258-21-4), a pharmacopoeial impurity reference standard (molecular formula C16H14N2O7, MW 346.29 g/mol) used for the identification and quantification of trace impurities in APIs.

Nicardipine Impurity 25 (C16H14N2O7) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Nicardipine Impurity 25 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H14N2O7
Molecular Weight346.29 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1978
Nitrogen Atoms2

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