Iopromide EP Impurity B CAS 76350-28-2
| CAS No. | 76350-28-2 |
| Molecular Formula | C17H22I3N3O7 |
| Molecular Weight | 761.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Iopromide EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Iopromide EP Impurity B (CAS 76350-28-2), a pharmacopoeial impurity reference standard (molecular formula C17H22I3N3O7, MW 761.09 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution, Iopromide EP Impurity B is typically off-white to pale yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 761.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H22I3N3O7 |
| Molecular Weight | 761.09 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Iopromide Standards
- Iopromide EP Impurity C (Mixture of Diastereomers) (CAS 154361-52-1)
- Iopromide Impurity 24 (CAS 1651211-76-5)
- Iopromide (CAS 73334-07-3)
- Iopromide Impurity 23 (CAS CATO-C4X-183223)
- Iopromide-[d3] (CAS 1189947-73-6)
- Iopromide impurity 16 (CAS CATO-C4X-183216)
- Iopromide EP Impurity A (CAS 154361-51-0)
- Iopromide EP Impurity G (Mixture of Diastereomers) (CAS 154361-53-2)
Recommended Standards
- Iomeprol Impurity 14 (CAS CATO-C4X-182014)
- Triacontyl docosanoate (CAS 80252-39-7)
- Eosin-5-maleimide (CAS 150322-02-4)
- Butyltrihexadecylsilane (CAS 18822-41-8)
- Chlortetracycline EP Impurity G (CAS 769895-23-0)
- Amitriptyline EP Impurity C (CAS 894-71-3)
- Baricitinib Impurity 64 (CAS 1187594-34-8)
- tert-butyl 4-[(4-bromo-1-methyl-1H-pyrazol-5-yl)carbonyl]piperazine-1-carboxylate (CAS 1005556-39-7)
- 4,6-Diiodopyrimidine (CAS 19646-06-1)
- N-((5-(aminomethyl)furan-2-yl)methyl)-N-propylpropan-1-amine (CAS 1170183-16-0)
- 9-(4-Aminophenyl)-9H-purin-6-amine (CAS 863675-87-0)
- 4-(Difluoromethoxy)-3-fluoro-2-methoxyphenol (CAS 2385503-22-8)
- Elobixibat Impurity 33 (CAS CATO-C4X-283833)
- Allo-Thr5-Tirzepatide (CAS CATO-CPTD788934)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com