Procaine Impurity N3 CAS 769864-93-9(free base)
| CAS No. | 769864-93-9(free base) |
| Molecular Formula | C7H5Cl2NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Procaine Impurity N3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Procaine Impurity N3 (CAS 769864-93-9(free base), C7H5Cl2NOHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Procaine Impurity N3 (C7H5Cl2NOHCl) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 226.48 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C7H5Cl2NO HCl |
| Molecular Weight | 226.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Procaine Standards
Recommended Standards
- Droperidol EP Impurity D (CAS 466118-75-2)
- Cefprozil (Z)-Isomer Impurity 44 (CAS CATO-C4X-149244)
- Sunitinib Impurity 18 (CAS 326914-17-4)
- 2-Ethyl-2,4,5-trimethyl-1,3-dioxolane (CAS 4359-51-7)
- Encorafenib Impurity 13 (CAS CATO-C4X-324913)
- Methyl 2-Bromooctanoate (CAS 5445-22-7)
- 4-Cyclopropoxy-N,N,2-trimethylpyridin-3-amine (CAS 1243447-04-2)
- 4-Hydroxy-4-(1-methyl-1H-pyrazol-4-yl)cyclohexan-1-one (CAS 1351990-15-2)
- Tert-butyl (cyclopropylmethyl)(piperidin-4-yl)carbamate (CAS 895541-77-2)
- Semaglutide impurity 37 (CAS CATO-C4X-222637)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com