Ataluren Impurity N CAS 775304-56-8
| CAS No. | 775304-56-8 |
| Molecular Formula | C15H9FN2O3 |
| Molecular Weight | 284.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ataluren Impurity N meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Ataluren Impurity N (CAS 775304-56-8, C15H9FN2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ataluren Impurity N (C15H9FN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 284.24 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C15H9FN2O3 |
| Molecular Weight | 284.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Ataluren Standards
- Ataluren (CAS 775304-57-9)
- Ataluren Impurity 6 (CAS 775304-58-0)
- Ataluren Impurity 3 (CAS CATO-C4X-30063)
- Ataluren Impurity 10 (CAS CATO-C4X-300610)
- Ataluren Impurity 11 (CAS CATO-C4X-300611)
- Ataluren Impurity 14 (CAS CATO-C4X-300614)
- Ataluren Impurity 5 (CAS 775304-28-4)
- Ataluren Impurity 7 (CAS 775303-92-9)
Recommended Standards
- N-((1,3,4-Thiadiazol-2-yl)carbamoyl)-2,6-difluorobenzamide (CAS 585570-24-7)
- 6-(4-Fluorophenyl)-[1,3]dioxolo[4,5-g]quinazolin-8(5H)-one (CAS 656833-95-3)
- Olaparib Impurity 37 (CAS 1423030-11-8)
- 4-Bromo-N,N-dibutylaniline (CAS 53358-54-6)
- DA-302168S Impurity 2 (CAS CATO-C3D-263269)
- Dopamine Impurity 105 (CAS CATO-C4X-1908105)
- Piperacillin Impurity 27 (CAS 67275-27-8)
- 6-((Tetrahydrofuran-3-yl)oxy)hexane-1-sulfonyl chloride (CAS 1342843-68-8)
- 3-Benzyl-2-((1E,3Z)-3-(3-benzyl-4-methylthiazol-2(3H)-ylidene)prop-1-en-1-yl)benzo[d]oxazol-3-ium bromide (CAS 68921-79-9)
- 2-Chloro-5-(chlorodifluoromethyl)pyridine (CAS 71701-84-3)
- (1R,2R)-2-(2-cyanophenyl)cyclopropane-1-carboxylic acid (CAS 2227758-80-5)
- 7-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylic acid (CAS 1086380-48-4)
- 4,5-Bis(benzyloxy)-2-methylbenzoic acid (CAS 127531-39-9)
- Peptide 431 (CAS CATO-CPTD788431)
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