Ataluren Impurity 11 CAS CATO-C4X-300611
| CAS No. | CATO-C4X-300611 |
| Molecular Formula | C16H11FN2O3 |
| Molecular Weight | 298.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Ataluren Impurity 11 (CAS CATO-C4X-300611, C16H11FN2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ataluren Impurity 11 (C16H11FN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 298.27 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C16H11FN2O3 |
| Molecular Weight | 298.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Ataluren Standards
- Ataluren Impurity 14 (CAS CATO-C4X-300614)
- Ataluren Impurity 5 (CAS 775304-28-4)
- Ataluren Impurity 4 (CAS CATO-C4X-30064)
- Ataluren Impurity 16 (CAS CATO-C4X-300616)
- Ataluren (CAS 775304-57-9)
- Ataluren Impurity N (CAS 775304-56-8)
- Ataluren Impurity 6 (CAS 775304-58-0)
- Ataluren Impurity 3 (CAS CATO-C4X-30063)
Recommended Standards
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- Olaparib Impurity 1 (CAS 763114-26-7)
- Dobutamine Impurity N1 (CAS 19713-28-1)
- Etrasimod Impurity 24 (CAS CATO-C4X-321424)
- Deoxycholic acid Impurity 38 (CAS CATO-C4X-335938)
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