2-Chloro-5-nitrobenzotrifluoride 5-nitro-2-chlorobenzotrifluoride 2-chloro-a,a,a-trifluoro-5-nitrotoluene 2-chloro-5-nitro-a,a,a-trifluorotoluene 1-chloro-4-nitro-2-trifluoromethyl-benzene 2-chloro-5-nitro benzotrifluoride 2-chloro-5-nitro-alpha,alpha,alpha-trifluorotoluene 1-chloro-2-(trifluoromethyl)-4-nitrobenzene 4-chloro-3-(trifluoromethyl)nitrobenzene 1-chloro-4-nitro-2-(trifluoromethyl)benzene 777-37-7 CAS 777-37-7

Purity 97%+In StockPharmaceutical Standards
CAS No.777-37-7
Molecular FormulaC7H9ClF3NO2
Molecular Weight231.60 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-5-nitrobenzotrifluoride
5-nitro-2-chlorobenzotrifluoride
2-chloro-a,a,a-trifluoro-5-nitrotoluene
2-chloro-5-nitro-a,a,a-trifluorotoluene
1-chloro-4-nitro-2-trifluoromethyl-benzene
2-chloro-5-nitro benzotrifluoride
2-chloro-5-nitro-alpha,alpha,alpha-trifluorotoluene
1-chloro-2-(trifluoromethyl)-4-nitrobenzene
4-chloro-3-(trifluoromethyl)nitrobenzene
1-chloro-4-nitro-2-(trifluoromethyl)benzene
777-37-7 CAS 777-37-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 231.60 g/mol gives 2-Chloro-5-nitrobenzotrifluoride 5-nitro-2-chlorobenzotrifluoride 2-chloro-a,a,a-trifluoro-5-nitrotoluene 2-chloro-5-nitro-a,a,a-trifluorotoluene 1-chloro-4-nitro-2-trifluoromethyl-benzene 2-chloro-5-nitro benzotrifluoride 2-chloro-5-nitro-alpha,alpha,alpha-trifluorotoluene 1-chloro-2-(trifluoromethyl)-4-nitrobenzene 4-chloro-3-(trifluoromethyl)nitrobenzene 1-chloro-4-nitro-2-(trifluoromethyl)benzene 777-37-7 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Chloro-5-nitrobenzotrifluoride 5-nitro-2-chlorobenzotrifluoride 2-chloro-a,a,a-trifluoro-5-nitrotoluene 2-chloro-5-nitro-a,a,a-trifluorotoluene 1-chloro-4-nitro-2-trifluoromethyl-benzene 2-chloro-5-nitro benzotrifluoride 2-chloro-5-nitro-alpha,alpha,alpha-trifluorotoluene 1-chloro-2-(trifluoromethyl)-4-nitrobenzene 4-chloro-3-(trifluoromethyl)nitrobenzene 1-chloro-4-nitro-2-(trifluoromethyl)benzene 777-37-7 (CAS 777-37-7), molecular formula C7H9ClF3NO2 and molecular weight 231.60 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-Chloro-5-nitrobenzotrifluoride 5-nitro-2-chlorobenzotrifluoride 2-chloro-a,a,a-trifluoro-5-nitrotoluene 2-chloro-5-nitro-a,a,a-trifluorotoluene 1-chloro-4-nitro-2-trifluoromethyl-benzene 2-chloro-5-nitro benzotrifluoride 2-chloro-5-nitro-alpha,alpha,alpha-trifluorotoluene 1-chloro-2-(trifluoromethyl)-4-nitrobenzene 4-chloro-3-(trifluoromethyl)nitrobenzene 1-chloro-4-nitro-2-(trifluoromethyl)benzene 777-37-7 (C7H9ClF3NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Chloro-5-nitrobenzotrifluoride 5-nitro-2-chlorobenzotrifluoride 2-chloro-a,a,a-trifluoro-5-nitrotoluene 2-chloro-5-nitro-a,a,a-trifluorotoluene 1-chloro-4-nitro-2-trifluoromethyl-benzene 2-chloro-5-nitro benzotrifluoride 2-chloro-5-nitro-alpha,alpha,alpha-trifluorotoluene 1-chloro-2-(trifluoromethyl)-4-nitrobenzene 4-chloro-3-(trifluoromethyl)nitrobenzene 1-chloro-4-nitro-2-(trifluoromethyl)benzene 777-37-7 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC7H9ClF3NO2
Molecular Weight231.60 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityLight-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1957
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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