Nikethamide Impurity 14 CAS 77727-88-9

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.77727-88-9
Molecular FormulaC10H12N2O
Molecular Weight176.22 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Nikethamide Impurity 14 CAS 77727-88-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 176.22 g/mol gives Nikethamide Impurity 14 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Nikethamide Impurity 14 (CAS 77727-88-9), a pharmacopoeial impurity reference standard (molecular formula C10H12N2O, MW 176.22 g/mol) used for the identification and quantification of trace impurities in APIs.

Structurally, Nikethamide Impurity 14 (C10H12N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 176.22 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Nikethamide Impurity 14 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H12N2O
Molecular Weight176.22 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1979
Nitrogen Atoms2

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